STEP1: ABOUT SKINCANCER
Cause of cancer _ 2 cases
1.Cell growth doesn’t stop
2.Disorder of apoptosis
p53 : Tumor repressor gene
P53 : transcription factor
Functions
-p53 are that first arrest cell cycle so control cell growth, also active apoptosis suicide program
P53 mutation ->p53 sytem breaks down, it can’t act as Transcriptor factor-> generating tumor
1. 피부의 기능
• 외상(trauma)과 감염(infection)에 대한 저항
- 피부 보호막은 산성막(acid mantle)이라 불림 => 산성(pH4~6)
• 다른 장벽 기능(other barrier functions)
- 물에 대한 장벽 (과도한 물을 흡수와 손실을 예방)
- 자외선에 대한 장벽, 해로운 약품에 대한 방어벽
• 비타민 D 합성(vitamin D synthesis)
- 피부
skin cells
Aug, 2006, Pro. Yamanaka ’s laboratory in Kyoto produced ‘pluripotent cells’
Nov, 2007, the first Human iPS cells
iPS cells are a type of pluripotent stem cell
artificially derived from a differentiated cell,
by inducing a “forced” expression of Certain genes!
Mechanism of
cancer production
①disorder of protein gene that sets ‘breaks’ to i
2-2. Changes
터키에서 유럽대륙으로 퍼져 나간 커피는 비약적인 발전을 이루게 된다.
최초의 커피숍이 생겨난 곳은 13세기경 아라비아의 성지 메카라고 알려지고 있다. 그만큼커피는 중동 지방의 이슬람을 통하여 점차 세계로 전파되어 나갔다. 특히 이슬람의 순례를 통하여 급격하게 전파되었으며 특
1. Introduction
The era we live in has various types of advertisement methods. Among the many advertisements, we focused on the TV, Online, Paper and Outdoor advertisement. The example cases of these advertisements that we collected are focused on humor or fear appeal. The reason why we divided the advertisements into the two groups is because humor and fear appeal based advertisements have enti
Introduction
Nowadays, the method of chemotherapy + radiation is widely used because it is more effective for cancer cells than normal cells.
However, patient’s quality of life is directly related to the targeting ability of treatment, so that method has some side effects.
So finding less toxic agents and choosing a precise delivery system is a task currently important.
Regulation of nan
(2) Active targeting
Nanoparticle passive targeting can be enhanced by ‘active targeting’, where specific ligands (peptides, antibodies, aptamers, or small molecules) are attached to the nanoparticle surface to bind receptors/antigens overexpressed on cancer cells. Targeting increases accumulation in tumors and lessens exposure to healthy tissue, which can improve a toxic drug’'s therape
A. Limitations
So far we have seen a new approach of using stem cells for targeting cancer site and a new concept of
treatment. However it might seem fascinating, it is important to note that significant impediments remain
before the true potential of this novel therapy can be fully realized. Here in this section we are going to
mainly focus on the limitations of neural stem cells esp